Speaker Year: 2025

Exploring the Gut Microbiota’s Role in Cancer Development and Progression

Topic Dr. Naoko Ohtani will talk about “Exploring the Gut Microbiota’s Role in Cancer Development and Progression,” particularly regarding the gut-liver axis-mediated mechanism of liver cancer development. Summary Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) have emerged as major contributors to hepatocellular carcinoma (HCC). However, the precise mechanisms of how liver…

Understanding the Microbiota of Centenarians for Healthy Aging

Topic  Understanding the Microbiota of Centenarians for Healthy Aging Research Summary Koji Atarashi focuses on how discrete gut microbes and their metabolites educate the immune system and promote healthy longevity. Landmark contributions include: (i) identifying TH17-inducing consortia such as segmented filamentous bacteria; (ii) uncovering Clostridia species whose short-chain fatty acids expand Treg cells and reinforce…

Insights into the Microbiota-Gut-Brain Axis from Longevity Research

Topic Dr. Naito will talk about “Insights into the Microbiota-Gut-Brain Axis from Longevity Research” during our First Conjoint Meeting between ISM and RIKEN, which will take place from October 8-9 in Tokyo, Japan. Summary Dr. Naito presentation will provide an overview of the current findings on the microbiota-gut-brain axis, incorporating gut microbiota metabolite analysis, to…

Microbial Metabolites and Their Role in Cellular Senescence

Topic Microbial Metabolites and Their Role in Cellular Senescence. Research interests His research focuses on interaction between microbiota and host via co-metabolites, the molecular mechanism of infection immunity and aging from microbiota, developing original techniques for single-cell microbe for interactions in microbiota. He devoted himself to the mechanism and intervention strategy of aging from the…

Decoding the Skin’s Hidden Ecosystem: Microbiome and pH Gradients as Therapeutic Frontiers

Topic Decoding the Skin’s Hidden Ecosystem: Microbiome and pH Gradients as Therapeutic Frontiers. Summary Prof. Amagai will explore the dynamic interplay among the skin’s structural barriers, skin microbiome, and immune response. Special focus will be given to the three-stepwise pH layers of the stratum corneum, how these distinct zones contribute to barrier integrity and regulate…

A Microbiota-Derived Bile Acid Reprograms Alveolar Macrophages to Control Lung Inflammation

Dr. Tomasz Wypych from the Nencki Institute of Experimental Biology, Poland, will talk about “A Microbiota-Derived Bile Acid Reprograms Alveolar Macrophages to Control Lung Inflammation“. About Dr. Wypych: Dr. Wypych’s current research aims to unravel bidirectional interactions between the commensal microbiota and the host, which could be harnessed to treat inflammatory diseases. On the microbial…

Microbiota Medicine: Shaping the Future of Health

Presentation Title Microbiota Medicine: Shaping the Future of Health Summary Our medicine today follows a fixed and static approach—one disease, one drug—treating each organ separately. However, the microbiome is changing this perspective by revealing how different parts of the body are interconnected. We now recognize axes such as the gut-brain, gut-kidney, and gut connections. Microbiota…

Deciphering the interactions between gut microbiota and male fertility

Topic : Deciphering the interactions between gut microbiota and male fertility Summary : The number of infertile couples has been increasing steadily since the 80s, with 1 in 6 couples infertile worldwide currently. In 50% of these cases, the causes can be traced to men. However, the causes remain unknown in ~4 out of 10…