Butyrate, the Gut Barrier, and Healthy Aging: When Microbiome Metabolites Rescue Mitochondrial Decline
A new study led by María Mittelbrunn (Universidad Autónoma de Madrid / CBM-CSIC) suggests that butyrate, a short-chain fatty acid produced by gut microbes, can delay multi-organ decline and extend survival in mouse models of systemic mitochondrial dysfunction. Mitochondria are central to metabolism and tissue maintenance. When mitochondrial function collapses, organisms often develop multisystem disease…
