We are pleased to announce that Dr. Masahito Hosokawa from Waseda University, Japan will join Second Conjoint RIKEN – ISM 2026 as a speaker and give a presentation entitled “A single amplified genome catalog reveals the dynamics of mobilome and resistome in the human microbiome“.

Masahito Hosokawa, Professor at Waseda University and co-founder of bitBiome, Inc., will present how single-cell genomics is transforming our ability to decode strain-level complexity within human microbiomes and track the spread of antibiotic resistance.

The human microbiome harbors vast within-species diversity that shapes how resistance genes and mobile genetic elements move through microbial communities. Yet linking these elements to their specific bacterial hosts has remained a major challenge. Dr. Hosokawa’s work solves this by applying high-throughput single-cell genome sequencing to recover strain-resolved genomes directly from gut and skin microbiomes, creating an unambiguous connection between mobile elements and their host bacteria.

He will introduce frameworks that integrate single-cell genomics with metagenomics and long-read sequencing, and present a single-amplified genome catalog that enables systematic characterization of mobilome and resistome dynamics across microbial communities.

This talk demonstrates how single-cell genomics moves microbiome science from broad community profiling to precise, strain-level biological insight, laying the groundwork for more targeted microbiome interventions.

For more information about his talk: 
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